The ONI Blog

ONIee of the week - Continuous Improvement Manager

Posted by Chris Best on 10 Jul 2019

We're excited to reveal more about a day in the life here at ONI. This week we're talking to our Continuous Improvement Manager - James Cooney

 

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Topics: People

ONIee of the week - Research Scientist

Posted by Chris Best on 4 Jul 2019

We're excited to reveal more about a day in the life here at ONI. This week we're talking to one of our Research Scientists - Yaoyao

 

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Topics: People

The best fluorophores for PALM imaging

Posted by Anna Caballe on 1 Jul 2019

Photoactivated Localization Microscopy, or PALM imaging, is a super-resolution technique that relies on the random activation of fluorophores to spatially resolve molecular details (Betzig et al. 2006). In brief, upon activation with the adequate laser, a sparse number of fluorophores emit for a short period before bleaching. Because fluorophores are only activated at the same time in small numbers until all have emitted, it is possible to localize and track single molecules over time.

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Topics: Technical, Microscopy, Featured

ONIee of the week - Software Engineer

Posted by Chris Best on 26 Jun 2019

We're excited to reveal more about a day in the life here at ONI. This week we're talking to one of our Software Engineers - Adriana 

 

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Topics: People

ONIee of the week - Assistant Accountant

Posted by Chris Best on 19 Jun 2019

We're excited to reveal more about a day in the life here at ONI. This week we're talking to our Assistant Accountant - Abey Ali  

 

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Topics: People

Using dSTORM to study purified extracellular vesicles

Posted by Andras Miklosi on 11 Jun 2019

Cells release different types of small-sized membrane vesicles (from 30nm to 1000nm) as a way of communicating with other cells and remove unwanted cell contents; these vesicles are collectively known as extracellular vesicles (EVs). Here we share how we have optimized the imaging of purified EVs to study their size, content and behavior using super-resolution microscopy.

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Topics: Technical, Microscopy, Featured

ONIee of the week - Optical Production Technician

Posted by Chris Best on 11 Jun 2019

We're excited to reveal more about a day in the life here at ONI. This week we're talking to one of our Optical Production Technicians - Natalia 

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Topics: People

Our 9 tips to optimize your immunofluorescence staining

Posted by Anna Caballe on 15 May 2019

We have all been there, after spending a day or two fixing and staining your samples, the images don't look as good as expected, the signal is not optimal, and no obvious conclusion can be drawn from the data. We have put together some tips to help you optimize your immunofluorescence staining protocol and increase the signal-to-noise ratio in your samples. If you are unsure about how the technique works, we recommend you read our immunofluorescence guide first.

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Topics: Technical

The Art in Science Competition awards from SIU with ONI

Posted by Anna Caballe on 15 May 2019

The Science Innovation Union (SIU) at the University of Oxford hosted their first ever Art in Science Competition recently, with the aim to connect diverse scientific communities and provide scientists the chance of showcasing their research in the form of artwork. Sponsors, ONI, were at the award ceremony that took place on 10th May at the Department of Earth Science, University of Oxford. 

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Topics: Events

Impressions on ISEV2019: when the world of EVs met in Kyoto

Posted by Valerio Pereno on 10 May 2019

The International Society for Extracellular Vesicles (ISEV) annual conference took place in Kyoto from 24-28th April 2019. On behalf of the ONI team that had the pleasure to attend, I summarize here my impressions from the meeting, how the extracellular vesicles (EV) data generated at ONI was received and the latest developments taking place in the EV field.

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Topics: Events